Name of the laboratory: | Bioinformatics |
Phone: | (+994 12) 5102223 |
Fax: | (+994 12) 5102223 |
E-mail: | |
Head of the laboratory: | Corresponding member of ANAS Ilham Ayub Shahmuradov |
Staff: | senior researcher Amina Ulkar Abdulazimova researcher Hokuma Fikrat Guliyeva engineer-programmer Nigar Rizvan Hajiyeva junior researcher Afet Kamal Dadashova junior researcher Fidan Beybala Yusifova |
Main activity directions: | · Development of bioinformatics analysis tools · Organization, expression, and evolution of eukaryotic and prokaryotic genomes · Molecular genetic basis of human diseases |
Main scientific achievements: | · To search for transcription start sites and regulatory elements, pre-mRNA polyadenylation sites in human, animal, and higher plant genomes, various computer analysis tools of high accuracy (PromH, PromHP, TSSP-TCM, nsite, nsiteM, nsiteH, POLYAR), as well as PlantProm database of plant RNA polymerase II promoters have been developed.
· In Arabidopsis and rice, it was revealed that the non-stop transcription of neighbor nuclear genes located in the “Tail-to-Head manner and the following alternative splicing and translation of the corresponding transcripts may produce chimeric polypeptides.
· Distribution spectrum and scale of DNA sequences of the plastid and mitochondrion origin in the nuclear genomes of various higher plants (Arabidopsis, rice, wine grape, black cottonwood, corn, sorghum) was clarified, as well as some facts indicating the expression of some intact nuclear copies of plastid and mitochondrial genes were revealed. |