Aytan Gabil Aghayeva

Place of birth

Ganja, Azerbaijan

Date of birth

01.09.1989

Education

Faculty of Biology, Baku State University

Scientific degree

Doctor of Philosophy in Biology

Academic rank

Speciality code and title for PhD thesis

2415.01

Molecular biology

Study of bacteria isolated from oil-contaminated soils of Azerbaijan for antibiotic activity

Total number of printed scientific publications

33

Number of scientific publications printed abroad

2

Number of papers published in journals indexed and abstracted in international databases

3 (Web of Science, SCOPUS, RSCİ, AGRİS)

Number of patents and certificates of authorship

Staff training:

-          number of PhD

Key scientific achievements

1.      28 strains of bacteria possessing antibacterial activity and belonging to 12 species have been isolated from the microbiota of oil-contaminated soils of Azerbaijan. On their basis, a specific collection called "producers of antimicrobial compounds" has been created.

2.      For the first time, the antibacterial activity of bacteria belonging to the species Bacillus vallismortis has been revealed. It is shown that B. vallismortis strain AZ-130 has high activity in the supernatant against Gram-positive opportunistic bacteria and produces one compound with antibacterial activity, the retention time (Rt) of which in the HPLC column is 12,648 min.

3.      The AZ-130 biomolecule is stable at low pH and is soluble in an organic solvent. The approximate molecular mass of the bioactive AZ-130 molecule is 3319,6 Da. A search in the APD3 database showed that there are currently no known antimicrobial compounds with a molecular mass of 3319,6 Daltons produced by B. vallismortis bacteria, which confirms that the compound obtained is new to science in general.

4.      It has been shown that the partially purified AZ-130 antibacterial compound at a concentration of 8 µg/mL to 16 µg/mL inhibits the growth and development of a methicillin-resistant strain of Staphylococcus aureus.

5.      It has been shown that non-traditional and poorly analyzed for the presence of strains with antimicrobial activity soils, such as oil-contaminated soils, can serve as a good source of bacteria producing antimicrobial compounds.

Titles of publications

1.Aytan Aghayeva, Nurana Huseynova (2026). Characterization of Soil Bacterial Isolates from the City of Shusha With Emphasis on Antimicrobial Activity and Molecular Features. Republican Scientific-Practical Conference "Innovative approaches in the study and efficient use of natural resources, agro-industrial wastes" dedicated to the 103rd anniversary of the birth of the Great Leader Heydar Aliyev. Ganja, May 14-15, 2026.

2.Aytan Aghayeva, Ilaha Hagverdiyeva (2026).  Soil Microbiota and Antimicrobial Activity: Functional and Molecular Analysis of Bacterial Isolates From Shusha City. Republican Scientific-Practical Conference "Innovative approaches in the study and efficient use of natural resources, agro-industrial wastes" dedicated to the 103rd anniversary of the birth of the Great Leader Heydar Aliyev. Ganja, May 14-15, 2026.

3.Aytan Aghayeva, Nurana Huseynova (2025). Creation of a bacterial library based on strains isolated from soil samples collected in the Jidir Plain of Shusha city and their morphological characterization. International conference “Toward the challenges in energy, food, environment, and climate security (EFEC 2025)”. Baku, October 15-17, 2025, p. 157.

4.Aytan Aghayeva, Ilaha Hagverdiyeva (2025).  Isolation and morphological characterization of bacterial species from soil samples collected at the İsa Spring in the city of Shusha. International conference “Toward the challenges in energy, food, environment, and climate security (EFEC 2025)”. Baku, October 15-17, 2025, p. 117.

5.Aytan Aghayeva, Stephen Streatfield (2025). Antibacterial Efficacy of a novel antimicrobial compound produced by Bacillus vallismortis strain AZ-130 isolated from oil contaminated soil sample in Azerbaijan. International conference “Toward the challenges in energy, food, environment, and climate security (EFEC 2025)”. Baku, October 15-17, 2025, p. 84-85.

6.Aghayeva Aytan, Huseynova Irada, Streatfield Stephen (2025). Determination of the minimum inhibitory concentration (MIC) of the AZ-130 compound against various pathogenic strains. Application of digital and GWAS-based technologies for the wheat improvement. International conference & Field workshop. Baku-Gobustan, June 12-13, 2025, p. 46-47.

7.G.T. Yusifova, A.G. Aghayeva (2024). Optimizing environmental conditions for enhanced interleukin production in Nicotiana benthamiana and Nicotiana tabacum: insights and strategies. Transactions of the Institute of Molecular Biology & Biotechnologies, 2024, vol. 8 № 2, p. 19-29.

8.Aytən Ağayeva, İradə Hüseynova, Stiven Stritfild (2024). Azərbaycanın neftlə çirklənmiş torpaqlarından ayrılmış AZ-130 ştamı tərəfindən sintez edilən AZ-130 bioaktiv maddəsinin kimyəvi quruluşu. “Azərbaycanda ətraf mühitin sağlamlaşdırılmasında Ümummilli Lider Heydər Əliyevin rolu” mövzusunda elmi-praktiki konfrans. Bakı, 23-24 may, 2024, s. 269.

9.Aytən Ağayeva, İradə Hüseynova, Stiven Stritfild (2023). AZ-130 birləşməsinin kimyəvi quruluşunun tədqiqi. “Heydər Əliyev və müasir biologiya elminin inkişafı: uğurlar və çağırışlar” mövzusunda beynəlxalq konfrans, 19-20 dekabr 2023-cü il, s. 87.

10.Aghayeva A.G., Streatfield S.J., Huseynova I.M. (2023). Comparative analysis of the activity of AZ-130 and B. subtilis supernatants against Lactococcus lactis. Journal of Life Sciences and Biomedicine, 2023, vol. 5(78), № 2, p. 44-48.

11.Aytan Aghayeva, Irada Huseynova (2023). Study of the stability of AZ-130 biomolecule at low ph values. “Heydər Əliyev və Azərbaycan Təbiəti” mövzusunda beynəlxalq konfrans. Bakı, 19-20 iyun, 2023, s. 143.

12.Aytən Ağayeva, Vidadi Yusibov (2022). AZ-130 birləşməsinin Lactococcus lactis bakteriyasına qarşı aktivliyinin tədqiqi. “Şuşa və ətraf ərazilərin biomüxtəlifliyi, torpaq və su ehtiyatları: gələcəyə baxış” mövzusunda beynəlxalq konfrans (hibrid formatda), Bakı, 22-24 sentyabr 2022, s. 397.

13.A.G. Aghayeva, S.J. Streatfield, I.M. Huseynova (2022). Influence of the AZ-130 biomolecule on the growth kinetics of the methicillin-resistant S. aureus strain. Transactions of the Institute of Molecular Biology & Biotechnologies, ANAS, 2022, vol. 6, № 1, p. 12-15.

14.Aytan Aghayeva (2022). Study of the presence of the subtilin gene in the AZ-130 strain. Karabakh III International Congress of Applied Sciences "Year of Shusha- 2022", Karabagh/Azerbaijan online and face-to-face participation, June 7-10, 2022, proceeding book volume 2, p. 3.

15.Aytan Aghayeva, Vidadi Yusibov, Irada Huseynova (2022). Organic extraction of biomolecule produced by the AZ-130 strain. AGRO International Conference on Agriculture, June 04-06, 2022, p. 451.

16.A.G. Aghayeva, S.J. Streatfield, I.M. Huseynova (2022). Study of the molecular mass of AZ-130 biomolecule and its stability at low pH. Journal of Life Sciences and Biomedicine, 2022, vol. 4 (77), № 1, p. 40-45.

17.А.Г. Агаева, С.Дж. Стритфилд, И.М. Гусейнова (2021). Штамм AZ-130 из нефтезагрязненной почвы Азербайджана: изоляция, антибактериальный скрининг и оптимизация условий культивирования. Микробиология, 2021, том 90, № 6, с. 718–727. DOI: 10.31857/S0026365621060033.

A.G. Aghayeva, S. J. Streatfield, I. M. Huseynova (2021). AZ-130 Strain from Oil-contaminated Soil of Azerbaijan: Isolation, Antibacterial Screening, and Optimization of Cultivation Conditions. Microbiology, 2021, vol. 90, № 6, p. 754–762. DOI: 10.1134/S0026261721060035.

18.A.G. Aghayeva, S.J. Streatfield, I.M. Huseynova (2021). Growth kinetics of AZ-130 strain isolated from oil-polluted soil sample of Azerbaijan for antimicrobial production. Transactions of the Institute of Molecular Biology & Biotechnologies, ANAS, 2021, vol. 5, p. 7-10.

19.Aytan Aghayeva (2021). Antibacterial properties of AZ-130 strain isolated from oil contaminated soil sample in Azerbaijan. First International Bilateral Workshop on Science Between Dokuz Eylül University and Azerbaijan National Academy of Sciences, 19 November, 2021, p. 7.

20.А.Г. Агаева, И.М. Гусейнова, С.Дж. Стритфилд (2021). Скрининг бактерий с антибактериальной активностью против Bacillus subtilis и Escherichia coli штаммов, несущих плазмиды обеспечивающие устойчивость к известным антибиотикам. Современная наука: актуальные проблемы теории и практики: Серия «Естественные и Технические науки», 2021, № 7, c. 7-11.

21.A.G. Aghayeva, L.Y. Babayeva, I.M. Huseynova (2021). Detection and molecular identification of Escherichia coli strains in water resources in Azerbaijan. Online Conference “Karabakh's biodiversity, land and water resources: past, present and future”, Baku, 20-21 May, 2021, p. 143.

22.A.G. Aghayeva, L.Y. Babayeva (2021). Detection of bacterial and fungal species in water resources in Azerbaijan. X International Conference on "Scientific Advances and Challenges in Biology", BSU, Baku, 6-7 May, 2021, p. 85-87.

23.A.Q. Ağayeva (2020). SARS-CoV-2 virusuna qarşı kli̇ni̇k və prekli̇nik tədqi̇qatlar mərhələsi̇ndə olan vaksi̇n və dərman preparatları. Koronavirus pandemiyası: elmi tədqiqatlardan sağlam gələcəyin təminatına doğru” mövzusunda beynəlxalq onlayn konfrans, Bakı, Azərbaycan, 04 - 05 avqust, 2020, s. 27-28.

24.A.Q. Ağayeva, V.M. Yusibov, İ.M. Hüseynova (2020). Azərbaycan torpaqlarından ayrılmış bakteriya ştamm kolleksiyasının yaradılması və onların yeni̇ biomolekullar üçün skri̇ni̇nqi̇. Koronavirus pandemiyası: elmi tədqiqatlardan sağlam gələcəyin təminatına doğru” mövzusunda beynəlxalq onlayn konfrans, Bakı, Azərbaycan, 04 - 05 avqust, 2020, s. 76-77.

25.А.Г. Агаева (2019). Создание бактериальной коллекции на основе штаммов, изолированных из почв Азербайджана и их скрининг на наличие новых антибактериальных биомолекул. Journal of Life Sciences and Biomedicine, 2019, vol. 1 (74), № 2, c. 13-19.

26.A.G. Aghayeva (2019). Optimization of culture conditions for higher production of antimicrobial compounds by AZ-130 bacterial strain isolated from soil of Azerbaijan. Journal of Life Sciences and Biomedicine, 2019, vol. 1 (74), № 1, p. 69-76.

27.Aytan Aghayeva, Vidadi Yusibov, Irada Huseynova (2019). Bacterial isolation and screening for the identification of novel antimicrobial compounds. 2nd International Conference on “One Health: Problems & Solutions”, Khazar University, Baku, Azerbaijan, 24-25 May, 2019, p. 97-98. (Oral Presentation).

28.Aytan Aghayeva, Vidadi Yusibov, Irada Huseynova (2019). Microbial mining for the identification of novel antimicrobial compounds. 1st Republic Students Scientific Conference on "Advances in Chemistry and Chemical Engineering" dedicated to the 96th anniversary of the national leader of Azerbaijan, Heydar Aliyev, Baku Higher Oil School, Baku, Azerbaijan, 15 - 19 April, 2019, p. 101-102. (Oral Presentation).

29.Aytan Aghayeva, Stephen Krasucki, Ansgar Flammersfeld, Irada Huseynova, Vidadi Yusibov and Charles M. Morris (2016). Microbial Mining for the Identification of Novel Biomolecules. “New Technologies, New Vaccines (NTNV)”, Wilmington, DE, USA, March, 2016, p. 55. (Poster Presentation).

30.Aghayeva A.Q., Sultanova N.F., Quliyeva F.B. (2013). Histochemical evidence for generation of active oxygen species in leaf tissues of virus-infected plants.  «New cells, New vaccines VII. From protein to product», Wilmington, DE, USA, 2013. (Poster Presentation).          

31.Farida Guliyeva, Aytan Agayeva, Nargiz Sultanova (2012). Molecular detection of tomato-infecting begomovirus (TYLCV) in Azerbaijan. «New cells, New vaccines VI. Target to Market», Wilmington, DE, 2012. (Poster Presentation).

32.А.Г. Агаева, Н.Ф. Султанова (2012). Молекулярная диагностика вируса желтой курчавости листьев томата методом RCA (Rolling Circle Amplification). Материалы Международной научной  конференции  на тему «Müasir  Biologiyanın  İnnovasiya  Problemləri», посвященный 110-летию проф.  М.А. Ахундова, БГУ, Баку, 25-26 мая, 2012, с. 34-36.

33.Н.Ф. Султанова, А.Г. Агаева, И.М. Гусейнова (2012). Определение супероксид - аниона в инфицированных вирусами листьях овощных растений. Azərbaycan Elmi-Tədqiqat Əkinçilik İnstitunun Elmi Əsərləri məcmuəsi XXIII: Bakı, 2012, c. 117-121.

Membership in national, international, and foreign scientific organizations

Pedagogical activity

Baku State University (paid per hour)

Other activities

Awards and prizes

2014 – Certificate of Honor of the Azerbaijan National Academy of Sciences (2014)

2023 – 1st place in the "Young scientist and specialists" competition of the Institute of Molecular Biology and Biotechnologies of the Ministry of Science and Education of the Republic of Azerbaijan dedicated to the 100th anniversary of the Great Leader Heydar Aliyev

2023 – "Young Scientist of the Year" diploma of the Azerbaijan National Academy of Sciences

Place of work and its address

Institute of Molecular Biology of MSE of the RA, AZ1073, Baku, Izzat Nabiyev str., 11

Presidium of ANAS, AZ1001, Baku, Istiglaliyyat str., 30

Position

Leading researcher

ANAS vice-presidents service, chief specialist

Office phone

Mobile

Home

Fax

e-mail

aytanaghayeva@gmail.com