HomeLaboratory of Molecular Bioengineering sa sa

Name of the laboratory:

Molecular Bioengineering

Phone:

(+994 12) 436 90 05

Fax:

(+994 12) 510 24 33 

E-mail:

Molecbioenglab@imbb.science.az

Head of the laboratory:

Corresponding member of ANAS Tarlan Hazarpasha Mammadov

Staff:

researcher Aysu-Shovkat Mahammad Hasanova

junior researcher Aytaj Ismayil Murshudzade

junior researcher Gunay Izaddin Zakiyeva

Research directions of the laboratory:

  • Development and application of the synthesis/production of therapeutically and industrially important recombinant proteins and enzymes in green plant leaves;
  • Development of ways to obtain high biomass, bioenergy, and biofuel production from green algae.

Main scientific achievements:

  • For the first time in the world, a cocktail vaccine candidate consisting of RBD (Receptor Binding Domain) and Nucleocapsid (N) proteins of SARS-CoV-2 virus against COVID-19 has been synthesized in sufficient quantities for commercialization in the Nicotiana benthamiana plant and preclinical studies have been completed. Meanwhile, as a potential therapeutic agent, recombinant human angiotensin-converting enzyme 2 (AGE2) variants with potent anti-SARS-CoV-2 activity have been successfully synthesized in Nicotiana benthamiana in quantities sufficient for commercialization, and preclinical studies have been completed;
  • For the first time, the presence of glycoproteins consisting of a sialic acid residue linked to 1,4-galactose in carbon dioxide-fixing green algal organisms was identified;
  • For the first time, the enzyme phosphoglycolate phosphatase, the main enzyme of photorespiration, was purified from the algae Clomidomanad reinhardtii and its nucleotide and amino acid sequences were read.