On November 15, the next scientific seminar was held at the Institute of Molecular Biology and Biotechnologies. Senior researcher of the Bioinformatics laboratory Amina Abdulazimova delivered a seminar on “Alternative initiation of transmission in eukaryotes” at the seminar. She provided an overview of new information in the literature on alternative initiation of transmission in eukaryotic organisms, cap-dependent and internal ribosome entry site (IRES), reverse splicing mechanisms, and the resulting circular mRNAs (circRNA). Circ mRNA is relevant in modern molecular biology for the regulation of physiological processes, the study of many diseases associated with mutations, including cancer, and the identification of tumor cells. These mRNAs are specific according to cells, tissues, and organs. A. Abdulazimova noted that modern research on the functional role and formation of circular RNAs is limited, and many questions remain open in this area.