The book “Pediatric surgery based on clinical cases” has been published by “Akademisyen Yayınevi” a publishing house in Turkey. The chapter entitled “The intersection of androgen insensitivity syndrome and anorectal malformations” was co-authored by Academician Irada Huseynova, acting Director of the Institute of Molecular Biology of the Ministry of Science and Education of the Republic of Azerbaijan and a doctoral researcher at the Institute and a pediatric surgeon at Chelsea and Westminster Hospital in London, United Kingdom Ilhama Jafarli.

This chapter reviews the genetic and clinical characteristics of androgen insensitivity syndrome, its underlying developmental mechanisms, and its potential associations with anorectal malformations. Studying this rare hereditary condition is important for gaining a deeper understanding of the mechanisms of hormonal signaling and improving individualized medical approaches.